On the cover!

A six-winged pinwheel?

This is the transcription termination factor Rho. It is a ring-shaped structure consisting of a hexamer that forms a tunnel in the center for the RNA (magenta) to pass through. When Rho attaches to the RNA polymerase (white and gray) during transcription, it uses this tunnel to pull the RNA out and terminate transcription at the appropriate time.

◎Credit:Lab for Transcription Structural Biology


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