Vol.14 – 2023 Autumn
On the cover! Rain clouds detected by radar? This is an image of proteins regulating genes in the cell nucleus. In an effort to reveal the behavior of genes in the nucleus of ES cells in two different states, the proteins, which are moving too rapidly to be captured by a camera, are manipulated to […]
Vol.13 – Summer 2023
On the cover! A six-winged pinwheel? This is the transcription termination factor Rho. It is a ring-shaped structure consisting of a hexamer that forms a tunnel in the center for the RNA (magenta) to pass through. When Rho attaches to the RNA polymerase (white and gray) during transcription, it uses this tunnel to pull the […]
Vol.12 – Winter 2023
A blue sun?
This is an aggregate of neural stem cells and the outflow of these cells from the aggregate. At high densities, neural stem cells align their elongated shapes and radially crawl out of the aggregate. Their weak clockwise cell motility becomes accentuated at the collective migration level, resulting in the appearance of a spiral formation that is visible to the naked eye.
Vol.11 – Summer 2022
A maze and a cave?
This is a heart of a newborn opossum (red). Opossums are marsupials, like kangaroos. Their hearts retain the ability to regenerate for at least two weeks after birth, which is the longest reported to date in mammals. The green cells are those currently proliferating.
Vol.10 – Spring 2022
On the cover: A growing baby corn? This is an electron microscope image of an olfactory sensillum found on the head of a fruit fly. Nanometer-sized (one-millionth of a millimeter) odorant molecules can pass through tiny pores (nanopores) on the sensillum surface to stimulate the nerves inside for detecting odors. In contrast, micrometer-sized (one-thousandth of […]
Vol. 09 – Winter 2022
Light blue hammock?
This is a graphic model of the three-dimensional structure of the DOCK-ELMO-Rac protein complex. DOCK (cyan) is involved in cell movement and maturation. The biological activities in the body are maintained by the binding and unbinding of proteins to other proteins.
Vol. 08 – Autumn 2021
Tangled roots of a tree?
This is a capillary network in the liver called sinusoids. The liver has a high regenerative capacity. It has been shown that when the liver is damaged, there is an increase in blood flow rate and …
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Vol. 07 – Spring 2021
Different fly species?
These are in fact all the same fruit fly species Drosophila melanogaster.
Their different appearances are due to one or multiple genetic mutations, which lead to black bodies, white eyes, etc. There is one wild-type (normal) fly and mutant flies with 20 different phenotypes. Can you identify them all?
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Vol.06 – Winter 2021
Floating bubbles?
These are 3D alveolar (lung) organoids or mini-organs generated from culturing mouse alveolar stem cells in a culture dish. The organoids can produce different types of alveolar cells.
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Vol.05 – Autumn 2020
Meadow of flowers in full bloom?
The initiation of cephalic furrow in the Drosophila embryo. This enigmatic structure appears only transiently and yet precisely during development.
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Vol.04 – Spring 2020
On the cover:
Cytochrome protein containing heme moving in water. Snapshot from a simulation calculated by supercomputer MDGRAPE-4A.
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Vol. 03 – Winter 2019
On the cover:
Inside view of a cell captured by electron microscopy. Structure in grey is the nucleus, and structures in yellow and other colors are mitochondria…
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Vol.02 – Summer 2019
On the cover:
3D microscopic images of C. elegans embryo. Nuclei of the approximately 350 cells in the embryo were labeled with a fluorescent marker …
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Vol.01 – Spring 2019
On the cover:
Hair follicle stem cells, which are important for hair shaft generation, secrete extracellular matrix proteins that guide the connections …
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